Flagship Pioneering

About the Company

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple transformative human health and sustainability products. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures.

The current Flagship ecosystem comprises over 40 companies, including Denali Therapeutics, Foghorn Therapeutics, Generate:Biomedicines, Inari, Indigo Agriculture, and Tessera Therapeutics.

Listed Jobs

Company Name

Flagship Pioneering

Job Title

Strategy and Business Development Lead (Vice President level)

Job Description

**Job title:** Strategy and Business Development Lead (Vice President) **Role Summary:** Senior executive charged with designing and executing the business development strategy for a subset of Flagship Pioneering’s ecosystem companies. Responsible for securing high-value partnerships and transactions with pharmaceutical and biotech partners, leveraging cross‑functional teams, and aligning BD initiatives with long‑term corporate growth plans. **Expactations:** - Minimum 12 years of industry experience with a proven track record of business development and corporate strategy leadership. - Demonstrated success in structuring sell‑side deals and partnering with pharma/biotech organizations. - Advanced degree (PhD or MD) strongly preferred; MBA is a plus. - Experience leading enterprise‑wide initiatives across multiple disciplines and organizational boundaries. **Key Responsibilities:** - Develop and own the BD strategy for designated portfolio companies, ensuring consistent deal flow. - Lead cross‑functional collaboration (R&D, IP, Finance, Legal, Strategy) to create partnerable packages and term sheets. - Conduct outreach, diligence, and negotiation with potential pharma and biotech partners. - Design data generation, research plans, exclusivity constructs, and partnership scopes in alignment with corporate goals. - Translate platform technology value into compelling narratives and key messaging for internal and external stakeholders. - Work closely with CEOs and senior leadership to embed BD plans into corporate strategy and long‑range planning. - Integrate partnership perspectives early in the R&D pipeline and evaluate early‑stage compounds for partnership potential. **Required Skills:** - Strategic planning and execution - Business development and partnership formulation - Negotiation and deal structuring - Cross‑functional leadership and stakeholder management - Deep understanding of biotech/pharma landscape - Strong analytical and data‑driven decision making - Excellent communication and presentation skills **Required Education & Certifications:** - PhD or MD in a relevant scientific field (strongly preferred) - MBA is advantageous - Minimum 12 years of relevant industry experience in business development, corporate strategy, or related executive roles.

Cambridge, United states

On site

Senior

02-12-2025

Company Name

Flagship Pioneering

Job Title

Director, AI Sciences

Job Description

**Job Title** Director, AI Sciences **Role Summary** Lead the development and production of AI/ML systems that enable target identification, validation, and drug development. Directed team of data scientists and engineers, set technical strategy, and collaborate closely with data infrastructure, assay development, biology validation, and discovery teams to drive end‑to‑end AI pipelines from method design to production deployment. **Expectations** - PhD (or equivalent) in genomics, computational biology, computer science, or related field. - 3–7 years of industry experience delivering AI/ML solutions for target discovery/drug development, fully owning projects from concept to production. - Proven leadership in a matrix environment; ability to mentor, scale a high‑performance team, and establish quality standards. - Strong software engineering habits: version control, CI/CD, containerization, automated testing. - Proficiency in Python, modern ML libraries (TensorFlow/PyTorch), cloud platforms (AWS) and modern data tooling (Spark, Kubernetes). - Ability to communicate complex results to both technical and non‑technical audiences. - Permission to work in the UK (Cambridge area; hybrid arrangements possible). **Key Responsibilities** 1. Define AI technical strategy and roadmap for the platform and drug discovery functions. 2. Lead, mentor, and grow the AI/ML team; maintain high standards for reproducibility and quality. 3. Partner with Data Infrastructure to model, version, and secure data schemas for ML training and inference. 4. Develop NGS‑based methods for target discovery and validation. 5. Build imaging AI pipelines for histology segmentation, detection, and classification, including weak/self‑supervised learning and rigorous model evaluation aligned with biological goals. 6. Create AI methods to accelerate target validation via standardized assays and support broader drug development timelines. 7. Translate results and recommendations into concise technical and business communications. **Required Skills** - Leadership & collaboration in cross‑functional, matrixed teams. - Deep expertise in Python and modern ML frameworks. - Cloud (AWS) architecture, containerization, CI/CD, and software quality practices. - Domain knowledge: genomics/NGS analysis, imaging AI for histology, and AI integration into target validation and drug discovery pipelines. - Strong analytical and problem‑solving abilities with a meticulous, detail‑oriented mindset. - Excellent written and verbal communication skills for technical and managerial audiences. **Required Education & Certifications** PhD or equivalent experience in genomics, computational biology, computer science, or a closely related discipline. No specific certifications required.

Cambridge, United kingdom

On site

Junior

15-02-2026